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Dr. med. Ali Sigaroudi

Dr. med. Ali Sigaroudi

Leitender Arzt Telemedizin
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Dr. med. Ali Sigaroudi kommt aus der Klinischen Pharmakologie und Toxikologie, Allgemeine Innere Medizin und Allgemeinmedizin, zuletzt war er Oberarzt Medizin im Spital Muri und auch im Spital Baden. In den Unikliniken Köln und Zürich begann er seine Forschung im Bereich Neuropharmakologie, Pharmakokinetik und -genetik. Seit mehreren Jahren befasst er sich mit der Entwicklung von Datenbanken bez. Medikamenteninteraktion. Aufgrund seiner fundierten Fachkentnisse leitet er ärztlich die Telemedizin.

Publikationen, Forschungsprojekte und Lehre

Publikationen

Originalarbeiten

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  1. Brockes M, Beck S, Sigaroudi A, Schulz E, Greis C, Brockes C, Telemonitoring kombiniert mit individueller telemedizinischer Beratung bei Hypertonikern mit antihypertensiver Therapie und unerwünschten Blutdruckschwankungen, Journal für Hypertonie - Austrian Journal of Hypertension 2025; 29 (1), 6-10

  2. Lucio M, Willkommen D, Schroeter M, Sigaroudi A, Schmitt-Kopplin P, Michalke B. Integrative Metabolomic and Metallomic Analysis in a Case-Control Cohort With Parkinson's Disease. Front Aging Neurosci. 2019 Dec 6;11:331.

  3. Sigaroudi A, Jetter A, Mueller TF, Kullak-Ublick G, Weiler S. Severe reduction in tacrolimus concentrations with concomitant metamizole (dipyrone) therapy in transplant patients. Eur J Clin Pharmacol. 2019 Jan 29

  4. Willkommen D, Lucio M, Moritz F, Forcisi S, Kanawati B, Smirnov KS, Schroeter M, Sigaroudi A, Schmitt-Kopplin P, Michalke B. Metabolomic investigations in cerebrospinal fluid of Parkinson's disease. PLoS One. 2018 Dec 10;13(12)

  5. Willkommen D, Lucio M, Schmitt-Kopplin P, Gazzaz M, Schroeter M, Sigaroudi A, Michalke B. Species fractionation in a case-control study concerning Parkinson's disease: Cu-amino acids discriminate CSF of PD from controls. J Trace Elem Med Biol. 2018 Sep;49:164-170

  6. Sigaroudi A, Kinzig M, Wahl O, Stelzer C, Schroeter M, Fuhr U, Holzgrabe U, Sörgel F. Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid: A Pharmacokinetic Assessment of Central Nervous System Adverse Effects. Pharmacology. 2018;102(3-4):133-137. Epub 2018 Jul 6

  7. Weber NT, Sigaroudi A, Ritter A, Boss A, Lehmann K, Goodman D, Farese S, Weiler S, Mueller TF. Intractable ascites associated with mycophenolate in a simultaneous kidney-pancreas transplant patient: a case report. BMC Nephrol. 2017 Dec 12;18(1):360

  8. Sigaroudi A, Kinzig M, Wahl O, Stelzer C, Schroeter M, Fuhr U, Holzgrabe U, Sörgel F. Quantification of Bisoprolol and Metoprolol in Simultaneous Human Serum and Cerebrospinal Fluid Samples. Pharmacology. 2017 Sep 21;101(1-2)

  9. Sigaroudi A, Stelzer C, Braun T, Frechen S, Hüttner S, Schröter M, Kinzig M, Fuhr U, Holzgrabe U, Sörgel F. Comparison of Pantoprazole Concentrations in Simultaneous Cerebrospinal Fluid and Serum Samples. Pharmacology. 2016 Apr 23;98(1-2):70-72

  10. Sigaroudi A, Kullak-Ublick GA, Weiler S. Concomitant administration of rifampicin and oxcarbazepine results in a significant decrease of the active MHD metabolite of oxcarbazepine. Eur J Clin Pharmacol. 2016 Mar;72(3):377-8

  11. Frechen S, Suleiman AA, Mohammad Nejad Sigaroudi A, Wachall B, Fuhr U. Population pharmacokinetic and pharmacodynamic modeling of epinephrine administered using a mobile inhaler. Drug Metab Pharmacokinet. 2015 Dec;30(6):391-9

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Weitere Publikationen

  1. Beck S, Brockes M, Sigaroudi A, Brockes C: Erfolgreiches Onboarding für effektive Betreuung zu Hause, ARS Medici, September 2024

  2. Ali Sigaroudi, PD Dr. med. Stefan Weiler. Heparininduzierte Thrombozytopenie Typ II. Swiss Med Forum 2017;17(33):676-677

  3. Ali Sigaroudi, Salome Zeller, Christoph Zeller. Neugeborenes mit SARS-CoV-2-Infektion. Swiss Med Forum. 2021;21(0910):163-164

 

Forschungsaktivitäten

  1. Quantification of Drugs and Their Degradation Products (ClinicalTrials.gov Identifier: NCT01828372), Uniklinik Köln, 2012-2016

  2. Quantification of Transition Metals (ClinicalTrials.gov Identifier: NCT02222779), Uniklinik Köln, 2013-2017

  3. Methylnaltrexone Pharmacokinetics in Neurointensive Care Patients (RELZH12, ClinicalTrials.gov Identifier: NCT01889290), Unispital Zürich, 2015-2018

  4. Hans Vollbrecht and Ali Sigaroudi developed Kisch.ch – a free accessible pharmacokinetic drug interaction table website containing phases I-III

 

Lehre

  1. Kleingruppenunterricht (POBL) während meiner Assistenzarztzeit in der Klinischen Pharmakologie 2012-2014n

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Kongressbeiträge (Vorträge / Poster)

  1. M. Brockes, S. Beck, A. Sigaroudi, E. Schulz, C. Greis, C. Brockes: Telemonitoring in Hypertensive Patients with Blood Pressure Fluctuations – A Pilot Study, SGAIM Basel, 21-23 May 2025

  2. Ali Sigaroudi, Patrick Richter, Christoph Zeller, Salome Zeller: Observational results of oropharyngeal swab tests for COVID-19 outpatients in Switzerland: a case series; SGAIM Basel, 19-21 May 2021

  3. Karl Nowak, Patrick Richter, Ali Sigaroudi: Inflammatory response mediated increase in vitamin k antagonist associated anticoagulation: a case report and literature review; SGAIM Basel, 19-21 May 2021

  4. 4th German Pharm Tox Summit 28 February 2019 in Stuttgart: “Kisch.ch – a pharmacokinetic drug interaction table containing Cytochrome P450, 89 Uridine 5’-diphospho-glucuronosyltransferase enzymes, P-gylcoprotein, breast cancer resistant protein, organic anion transporters, organic cation transporter and organic-anion-transporting polypeptides 1B, among other”

  5. 3rd German Pharm Tox-Summit, 1 March 2018 in Göttingen: “Severe reduction in tacrolimus concentrations with concomitant metamizole (dipyrone) therapy in five transplant patients”

  6. Life Sciences congress in Lausanne, Switzerland, 12-13 February 2018. “Kisch.ch – the first free accessible pharmacokinetic drug interaction table website containing phases I-III.

  7. Gesellschaft für Mineralstoffe und Spurenelemente (GMS) Jahrestagung, 28-30 September 2017 in Aachen, Germany. «Metals and metabolites in Cerebrospinal Fluid of Parkinson’s diesease patient», Willkommen, Desiree; Lucio, Marianna; Kanawati, Basem; Forcisi, Sara; Sigaroudi, Ali; Schroeter, Michael; Fuhr; Uwe; Schmitt-Kopplin, Philippe; Michalke, Bernhard.

  8. 2nd German Pharm Tox-Summit, 6-9 March 2017 in Heidelberg. “Comparison of hydrochlorothiazide and ramipril concentrations in simultaneous cerebrospinal fluid and blood serum samples”

  9. 20th Joint Meeting “Signal Transduction – Receptors, Mediators and Genes”, November 9-11, 2016 at the Leonardo Hotel Weimar. “Comparison of metoprolol and bisoprolol concentrations in simultaneous cerebrospinal fluid and blood serum samples

  10. 1st Spring Assembly of the Swiss Society for General Internal Medicine (SGAIM) from 25 – 27 May 2016 in Congress Center Basel; Five-minutes lecture: Pharmacokinetics of daily methylnaltrexone in neuro-intensive care patients with cerebral hemorrhage

  11. 16th annual congress for Clinical Pharmacology, 9.-10 October 2014, Cologne; Comparison of pantoprazole concentrations in simultaneous cerebrospinal fluid and serum samples

Kontakt

ali.sigaroudi@alcare.ch

+41 (0) 71 923 01 48

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